Vitamin D status associated with disability in MS
According to a 5 year observational study, increased vitamin D status is associated with decreased disability and increased preservation of grey matter in patients with multiple sclerosis.
The researchers assessed vitamin D serum levels, clinical disability, and MRI brain volumes annually in 491 patients with MS.
Dr Ellen Mowry and colleagues found that with every 10ng/ml increase in 25-hydroxyvitamin D level, subsequent normalized grey matter was 7cc higher, and expanded disability status scale (EDSS) scores were 0.05 points lower.
Dr Mowry is the lead investigator in a randomized treatment trial which will assess the efficacy of high and low dose vitamin D supplementation on attack rates, changes in brain volume, and appearance of new lesions in patients with relapsing-remitting MS.
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